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Clinical and metabolic effects associated with weight changes and obeticholic acid in non-alcoholic steatohepatitis
BACKGROUND: In a 72-week, randomised controlled trial of obeticholic acid (OCA) in non-alcoholic steatohepatitis (NASH), OCA was superior to placebo in improving serum ALT levels and liver histology. OCA therapy also reduced weight. AIMS: Because weight loss by itself can improve histology, to perfo...
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| Publicado no: | Aliment Pharmacol Ther |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5931362/ https://ncbi.nlm.nih.gov/pubmed/29333665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/apt.14492 |
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