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Clinical and metabolic effects associated with weight changes and obeticholic acid in non-alcoholic steatohepatitis
BACKGROUND: In a 72-week, randomised controlled trial of obeticholic acid (OCA) in non-alcoholic steatohepatitis (NASH), OCA was superior to placebo in improving serum ALT levels and liver histology. OCA therapy also reduced weight. AIMS: Because weight loss by itself can improve histology, to perfo...
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| Publicat a: | Aliment Pharmacol Ther |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5931362/ https://ncbi.nlm.nih.gov/pubmed/29333665 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/apt.14492 |
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