Dengue virus infection induces broadly cross-reactive human IgM antibodies that recognize intact virions in humanized BLT-NSG mice

The development of small animal models that elicit human immune responses to dengue virus (DENV) is important since prior immunity is a major risk factor for developing severe dengue disease. This study evaluated anti-DENV human antibody (hAb) responses generated from immortalized B cells after DENV...

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Detalhes bibliográficos
Publicado no:Exp Biol Med (Maywood)
Main Authors: Jaiswal, Smita, Smith, Kenneth, Ramirez, Alejandro, Woda, Marcia, Pazoles, Pamela, Shultz, Leonard D, Greiner, Dale L, Brehm, Michael A, Mathew, Anuja
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4446989/
https://ncbi.nlm.nih.gov/pubmed/25125497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370214546273
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