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Enhanced humoral and HLA-A2-restricted dengue virus-specific T-cell responses in humanized BLT NSG mice

Dengue is a mosquito-borne viral disease of humans, and animal models that recapitulate human immune responses or dengue pathogenesis are needed to understand the pathogenesis of the disease. We recently described an animal model for dengue virus (DENV) infection using humanized NOD-scid IL2rγ(null)...

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Autors principals: Jaiswal, Smita, Pazoles, Pamela, Woda, Marcia, Shultz, Leonard D, Greiner, Dale L, Brehm, Michael A, Mathew, Anuja
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3385033/
https://ncbi.nlm.nih.gov/pubmed/22384859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2012.03585.x
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