Superior Human Leukocyte Reconstitution and Susceptibility to Vaginal HIV Transmission in Humanized NOD-scid IL-2R (−/−) (NSG) BLT Mice

Humanized Bone marrow/Liver/Thymus (BLT) mice recapitulate the mucosal transmission of HIV, permitting study of early events in HIV pathogenesis and evaluation of preexposure prophylaxis methods to inhibit HIV transmission. Human hematopoiesis is reconstituted in NOD-scid mice by implantation of hum...

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Main Authors: Stoddart, Cheryl A., Maidji, Ekaterina, Galkina, Sofiya A., Kosikova, Galina, Rivera, Jose M., Moreno, Mary E., Sloan, Barbara, Joshi, Pheroze, Long, Brian R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3152643/
https://ncbi.nlm.nih.gov/pubmed/21684569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2011.05.013
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