Argonaute of the archaeon Pyrococcus furiosus is a DNA-guided nuclease that targets cognate DNA

Functions of prokaryotic Argonautes (pAgo) have long remained elusive. Recently, Argonautes of the bacteria Rhodobacter sphaeroides and Thermus thermophilus were demonstrated to be involved in host defense. The Argonaute of the archaeon Pyrococcus furiosus (PfAgo) belongs to a different branch in th...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Swarts, Daan C., Hegge, Jorrit W., Hinojo, Ismael, Shiimori, Masami, Ellis, Michael A., Dumrongkulraksa, Justin, Terns, Rebecca M., Terns, Michael P., van der Oost, John
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Nucleic Acid Enzymes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4446448/
https://ncbi.nlm.nih.gov/pubmed/25925567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv415
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