Role of free DNA ends and protospacer adjacent motifs for CRISPR DNA uptake in Pyrococcus furiosus

To acquire CRISPR–Cas immunity against invasive mobile genetic elements, prokaryotes must first integrate fragments of foreign DNA into their genomic CRISPR arrays for use in future invader silencing. Here, we found that the hyperthermophilic archaeaon, Pyrococcus furiosus, actively incorporates DNA...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Nucleic Acids Res
Päätekijät: Shiimori, Masami, Garrett, Sandra C., Chambers, Dwain P., Glover, Claiborne V. C., Graveley, Brenton R., Terns, Michael P.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2017
Aiheet:
Molecular Biology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5737086/
https://ncbi.nlm.nih.gov/pubmed/29036456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx839
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