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The RNA- and DNA-targeting CRISPR–Cas immune systems of Pyrococcus furiosus

Using the hyperthermophile Pyrococcus furiosus, we have delineated several key steps in CRISPR (clustered regularly interspaced short palindromic repeats)–Cas (CRISPR-associated) invader defence pathways. P. furiosus has seven transcriptionally active CRISPR loci that together encode a total of 200...

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Bibliografske podrobnosti
Main Authors: Terns, Rebecca M., Terns, Michael P.
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3996508/
https://ncbi.nlm.nih.gov/pubmed/24256230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20130056
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