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The RNA- and DNA-targeting CRISPR–Cas immune systems of Pyrococcus furiosus
Using the hyperthermophile Pyrococcus furiosus, we have delineated several key steps in CRISPR (clustered regularly interspaced short palindromic repeats)–Cas (CRISPR-associated) invader defence pathways. P. furiosus has seven transcriptionally active CRISPR loci that together encode a total of 200...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3996508/ https://ncbi.nlm.nih.gov/pubmed/24256230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20130056 |
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