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The Soluble Heparin-Binding EGF-Like Growth Factor Stimulates EGF Receptor Trafficking to the Nucleus

Most ligands of epidermal growth factor receptor (EGFR) have the ability to induce EGFR translocation into the nucleus, where EGFR acts as an important transcriptional regulator. Soluble form of heparin-binding EGF-like growth factor (sHB-EGF) is one of the ligands for EGFR in many cell types; howev...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Korotkevych, Nataliia V., Labyntsev, Andrii Ju., Kolybo, Denis V., Komisarenko, Serhiy V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4446362/
https://ncbi.nlm.nih.gov/pubmed/26016774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0127887
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