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The Soluble Heparin-Binding EGF-Like Growth Factor Stimulates EGF Receptor Trafficking to the Nucleus

Most ligands of epidermal growth factor receptor (EGFR) have the ability to induce EGFR translocation into the nucleus, where EGFR acts as an important transcriptional regulator. Soluble form of heparin-binding EGF-like growth factor (sHB-EGF) is one of the ligands for EGFR in many cell types; howev...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Korotkevych, Nataliia V., Labyntsev, Andrii Ju., Kolybo, Denis V., Komisarenko, Serhiy V.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4446362/
https://ncbi.nlm.nih.gov/pubmed/26016774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0127887
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