Transmembrane and soluble isoforms of heparin-binding EGF-like growth factor regulate distinct processes in the pancreas

BACKGROUND & AIMS: Heparin-binding epidermal growth factor-like growth factor (HB-EGF) is produced as a type I single pass transmembrane protein that can be cleaved to release a diffusible peptide. HB-EGF, often over-expressed in damaged or diseased epithelium, is normally expressed in pancreati...

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Detalhes bibliográficos
Main Authors: Ray, Kevin C., Blaine, Stacy A., Washington, M. Kay, Braun, Ada H., Singh, Amar B., Harris, Raymond C., Harding, Paul A., Coffey, Robert J., Means, Anna L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2767440/
https://ncbi.nlm.nih.gov/pubmed/19689925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2009.07.067
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