Heparin-Binding Epidermal Growth Factor-like growth factor eliminates constraints on activated Kras to promote rapid onset of pancreatic neoplasia

Pancreatic cancer remains one of the most deadly cancers with few treatment options at late stages and little information about how it develops through earlier stages. Activating mutation of the Kras gene has been implicated in, but is not sufficient for, tumorigenesis. In mouse models of pancreatic...

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Detalhes bibliográficos
Main Authors: Ray, Kevin C., Moss, Mary E., Franklin, Jeffery L., Weaver, Connie J., Higginbotham, James, Song, Yan, Revetta, Frank L., Blaine, Stacy A., Bridges, L. Richard, Guess, Katherine E., Coffey, Robert J., Crawford, Howard C., Washington, M. Kay, Means, Anna L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929321/
https://ncbi.nlm.nih.gov/pubmed/23376846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.3
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