Heparin-Binding Epidermal Growth Factor-like growth factor eliminates constraints on activated Kras to promote rapid onset of pancreatic neoplasia

Pancreatic cancer remains one of the most deadly cancers with few treatment options at late stages and little information about how it develops through earlier stages. Activating mutation of the Kras gene has been implicated in, but is not sufficient for, tumorigenesis. In mouse models of pancreatic...

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Autori principali: Ray, Kevin C., Moss, Mary E., Franklin, Jeffery L., Weaver, Connie J., Higginbotham, James, Song, Yan, Revetta, Frank L., Blaine, Stacy A., Bridges, L. Richard, Guess, Katherine E., Coffey, Robert J., Crawford, Howard C., Washington, M. Kay, Means, Anna L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3929321/
https://ncbi.nlm.nih.gov/pubmed/23376846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.3
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