Investigation of Soluble and Transmembrane CTLA-4 Isoforms in Serum and Microvesicles

Expression of the CTLA-4 gene is absolutely required for immune homeostasis, but aspects of its molecular nature remain undefined. In particular, the characterization of the soluble CTLA-4 (sCTLA-4) protein isoform generated by an alternatively spliced mRNA of CTLA4 lacking transmembrane-encoding ex...

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Bibliografische gegevens
Hoofdauteurs: Esposito, Laura, Hunter, Kara M. D., Clark, Jan, Rainbow, Daniel B., Stevens, Helen, Denesha, Jennifer, Duley, Simon, Dawson, Sarah, Coleman, Gillian, Nutland, Sarah, Bell, Gwynneth L., Moran, Carla, Pekalski, Marcin, Todd, John A., Wicker, Linda S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: AAI 2014
Onderwerpen:
Molecular and Structural Immunology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4082723/
https://ncbi.nlm.nih.gov/pubmed/24928993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1303389
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