Investigation of Soluble and Transmembrane CTLA-4 Isoforms in Serum and Microvesicles

Expression of the CTLA-4 gene is absolutely required for immune homeostasis, but aspects of its molecular nature remain undefined. In particular, the characterization of the soluble CTLA-4 (sCTLA-4) protein isoform generated by an alternatively spliced mRNA of CTLA4 lacking transmembrane-encoding ex...

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Detalhes bibliográficos
Main Authors: Esposito, Laura, Hunter, Kara M. D., Clark, Jan, Rainbow, Daniel B., Stevens, Helen, Denesha, Jennifer, Duley, Simon, Dawson, Sarah, Coleman, Gillian, Nutland, Sarah, Bell, Gwynneth L., Moran, Carla, Pekalski, Marcin, Todd, John A., Wicker, Linda S.
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2014
Assuntos:
Molecular and Structural Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4082723/
https://ncbi.nlm.nih.gov/pubmed/24928993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1303389
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