Investigation of Soluble and Transmembrane CTLA-4 Isoforms in Serum and Microvesicles

Expression of the CTLA-4 gene is absolutely required for immune homeostasis, but aspects of its molecular nature remain undefined. In particular, the characterization of the soluble CTLA-4 (sCTLA-4) protein isoform generated by an alternatively spliced mRNA of CTLA4 lacking transmembrane-encoding ex...

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Bibliografski detalji
Glavni autori: Esposito, Laura, Hunter, Kara M. D., Clark, Jan, Rainbow, Daniel B., Stevens, Helen, Denesha, Jennifer, Duley, Simon, Dawson, Sarah, Coleman, Gillian, Nutland, Sarah, Bell, Gwynneth L., Moran, Carla, Pekalski, Marcin, Todd, John A., Wicker, Linda S.
Format: Artigo
Jezik:Inglês
Izdano: AAI 2014
Teme:
Molecular and Structural Immunology
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4082723/
https://ncbi.nlm.nih.gov/pubmed/24928993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1303389
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