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Loss of mTOR signaling affects cone function, cone structure and expression of cone specific proteins without affecting cone survival
Cones are the primary photoreceptor (PR) cells responsible for vision in humans. They are metabolically highly active requiring phosphoinositide 3-kinase (PI3K) activity for long-term survival. One of the downstream targets of PI3K is the kinase mammalian target of rapamycin (mTOR), which is a key r...
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| Pubblicato in: | Exp Eye Res |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4446177/ https://ncbi.nlm.nih.gov/pubmed/25887293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exer.2015.04.006 |
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