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Activated mTORC1 promotes long-term cone survival in retinitis pigmentosa mice

Retinitis pigmentosa (RP) is an inherited photoreceptor degenerative disorder that results in blindness. The disease is often caused by mutations in genes that are specific to rod photoreceptors; however, blindness results from the secondary loss of cones by a still unknown mechanism. Here, we demon...

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Bibliografski detalji
Izdano u:J Clin Invest
Glavni autori: Venkatesh, Aditya, Ma, Shan, Le, Yun Z., Hall, Michael N., Rüegg, Markus A., Punzo, Claudio
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396488/
https://ncbi.nlm.nih.gov/pubmed/25798619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI79766
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