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Activated mTORC1 promotes long-term cone survival in retinitis pigmentosa mice

Retinitis pigmentosa (RP) is an inherited photoreceptor degenerative disorder that results in blindness. The disease is often caused by mutations in genes that are specific to rod photoreceptors; however, blindness results from the secondary loss of cones by a still unknown mechanism. Here, we demon...

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Dades bibliogràfiques
Publicat a:J Clin Invest
Autors principals: Venkatesh, Aditya, Ma, Shan, Le, Yun Z., Hall, Michael N., Rüegg, Markus A., Punzo, Claudio
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396488/
https://ncbi.nlm.nih.gov/pubmed/25798619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI79766
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