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Activated mTORC1 promotes long-term cone survival in retinitis pigmentosa mice

Retinitis pigmentosa (RP) is an inherited photoreceptor degenerative disorder that results in blindness. The disease is often caused by mutations in genes that are specific to rod photoreceptors; however, blindness results from the secondary loss of cones by a still unknown mechanism. Here, we demon...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Main Authors: Venkatesh, Aditya, Ma, Shan, Le, Yun Z., Hall, Michael N., Rüegg, Markus A., Punzo, Claudio
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396488/
https://ncbi.nlm.nih.gov/pubmed/25798619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI79766
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