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Activated mTORC1 promotes long-term cone survival in retinitis pigmentosa mice

Retinitis pigmentosa (RP) is an inherited photoreceptor degenerative disorder that results in blindness. The disease is often caused by mutations in genes that are specific to rod photoreceptors; however, blindness results from the secondary loss of cones by a still unknown mechanism. Here, we demon...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Venkatesh, Aditya, Ma, Shan, Le, Yun Z., Hall, Michael N., Rüegg, Markus A., Punzo, Claudio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4396488/
https://ncbi.nlm.nih.gov/pubmed/25798619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI79766
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