Rapid determination of anti-tuberculosis drug resistance from whole-genome sequences

Mycobacterium tuberculosis drug resistance (DR) challenges effective tuberculosis disease control. Current molecular tests examine limited numbers of mutations, and although whole genome sequencing approaches could fully characterise DR, data complexity has restricted their clinical application. A l...

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Detalhes bibliográficos
Publicado no:Genome Med
Main Authors: Coll, Francesc, McNerney, Ruth, Preston, Mark D, Guerra-Assunção, José Afonso, Warry, Andrew, Hill-Cawthorne, Grant, Mallard, Kim, Nair, Mridul, Miranda, Anabela, Alves, Adriana, Perdigão, João, Viveiros, Miguel, Portugal, Isabel, Hasan, Zahra, Hasan, Rumina, Glynn, Judith R, Martin, Nigel, Pain, Arnab, Clark, Taane G
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Method
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4446134/
https://ncbi.nlm.nih.gov/pubmed/26019726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-015-0164-0
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