Rapid determination of anti-tuberculosis drug resistance from whole-genome sequences

Mycobacterium tuberculosis drug resistance (DR) challenges effective tuberculosis disease control. Current molecular tests examine limited numbers of mutations, and although whole genome sequencing approaches could fully characterise DR, data complexity has restricted their clinical application. A l...

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Vydáno v:Genome Med
Hlavní autoři: Coll, Francesc, McNerney, Ruth, Preston, Mark D, Guerra-Assunção, José Afonso, Warry, Andrew, Hill-Cawthorne, Grant, Mallard, Kim, Nair, Mridul, Miranda, Anabela, Alves, Adriana, Perdigão, João, Viveiros, Miguel, Portugal, Isabel, Hasan, Zahra, Hasan, Rumina, Glynn, Judith R, Martin, Nigel, Pain, Arnab, Clark, Taane G
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
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Method
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4446134/
https://ncbi.nlm.nih.gov/pubmed/26019726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-015-0164-0
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