Rapid determination of anti-tuberculosis drug resistance from whole-genome sequences

Mycobacterium tuberculosis drug resistance (DR) challenges effective tuberculosis disease control. Current molecular tests examine limited numbers of mutations, and although whole genome sequencing approaches could fully characterise DR, data complexity has restricted their clinical application. A l...

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Veröffentlicht in:Genome Med
Hauptverfasser: Coll, Francesc, McNerney, Ruth, Preston, Mark D, Guerra-Assunção, José Afonso, Warry, Andrew, Hill-Cawthorne, Grant, Mallard, Kim, Nair, Mridul, Miranda, Anabela, Alves, Adriana, Perdigão, João, Viveiros, Miguel, Portugal, Isabel, Hasan, Zahra, Hasan, Rumina, Glynn, Judith R, Martin, Nigel, Pain, Arnab, Clark, Taane G
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4446134/
https://ncbi.nlm.nih.gov/pubmed/26019726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-015-0164-0
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