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Detection of Cytosine Methylation in Ancient DNA from Five Native American Populations Using Bisulfite Sequencing

While cytosine methylation has been widely studied in extant populations, relatively few studies have analyzed methylation in ancient DNA. Most existing studies of epigenetic marks in ancient DNA have inferred patterns of methylation in highly degraded samples using post-mortem damage to cytosines a...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Smith, Rick W. A., Monroe, Cara, Bolnick, Deborah A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445908/
https://ncbi.nlm.nih.gov/pubmed/26016479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125344
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