Detection of Cytosine Methylation in Ancient DNA from Five Native American Populations Using Bisulfite Sequencing

While cytosine methylation has been widely studied in extant populations, relatively few studies have analyzed methylation in ancient DNA. Most existing studies of epigenetic marks in ancient DNA have inferred patterns of methylation in highly degraded samples using post-mortem damage to cytosines a...

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Bibliographic Details
Published in:PLoS One
Main Authors: Smith, Rick W. A., Monroe, Cara, Bolnick, Deborah A.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445908/
https://ncbi.nlm.nih.gov/pubmed/26016479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125344
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