Low expression levels of hepsin and TMPRSS3 are associated with poor breast cancer survival

BACKGROUND: Hepsin, (also called TMPRSS1) and TMPRSS3 are type II transmembrane serine proteases (TTSPs) that are involved in cancer progression. TTSPs can remodel extracellular matrix (ECM) and, when dysregulated, promote tumor progression and metastasis by inducing defects in basement membrane and...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Pelkonen, Mikko, Luostari, Kaisa, Tengström, Maria, Ahonen, Hermanni, Berdel, Bozena, Kataja, Vesa, Soini, Ylermi, Kosma, Veli-Matti, Mannermaa, Arto
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445813/
https://ncbi.nlm.nih.gov/pubmed/26014348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1440-5
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