Low expression levels of hepsin and TMPRSS3 are associated with poor breast cancer survival

BACKGROUND: Hepsin, (also called TMPRSS1) and TMPRSS3 are type II transmembrane serine proteases (TTSPs) that are involved in cancer progression. TTSPs can remodel extracellular matrix (ECM) and, when dysregulated, promote tumor progression and metastasis by inducing defects in basement membrane and...

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Detaylı Bibliyografya
Yayımlandı:BMC Cancer
Asıl Yazarlar: Pelkonen, Mikko, Luostari, Kaisa, Tengström, Maria, Ahonen, Hermanni, Berdel, Bozena, Kataja, Vesa, Soini, Ylermi, Kosma, Veli-Matti, Mannermaa, Arto
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2015
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445813/
https://ncbi.nlm.nih.gov/pubmed/26014348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1440-5
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