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Low expression levels of hepsin and TMPRSS3 are associated with poor breast cancer survival

BACKGROUND: Hepsin, (also called TMPRSS1) and TMPRSS3 are type II transmembrane serine proteases (TTSPs) that are involved in cancer progression. TTSPs can remodel extracellular matrix (ECM) and, when dysregulated, promote tumor progression and metastasis by inducing defects in basement membrane and...

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發表在:BMC Cancer
Main Authors: Pelkonen, Mikko, Luostari, Kaisa, Tengström, Maria, Ahonen, Hermanni, Berdel, Bozena, Kataja, Vesa, Soini, Ylermi, Kosma, Veli-Matti, Mannermaa, Arto
格式: Artigo
語言:Inglês
出版: BioMed Central 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445813/
https://ncbi.nlm.nih.gov/pubmed/26014348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1440-5
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