Low expression levels of hepsin and TMPRSS3 are associated with poor breast cancer survival

BACKGROUND: Hepsin, (also called TMPRSS1) and TMPRSS3 are type II transmembrane serine proteases (TTSPs) that are involved in cancer progression. TTSPs can remodel extracellular matrix (ECM) and, when dysregulated, promote tumor progression and metastasis by inducing defects in basement membrane and...

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Publicado en:BMC Cancer
Main Authors: Pelkonen, Mikko, Luostari, Kaisa, Tengström, Maria, Ahonen, Hermanni, Berdel, Bozena, Kataja, Vesa, Soini, Ylermi, Kosma, Veli-Matti, Mannermaa, Arto
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2015
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445813/
https://ncbi.nlm.nih.gov/pubmed/26014348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1440-5
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