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Full length and protease domain activity of chikungunya virus nsP2 differ from other alphavirus nsP2 proteases in recognition of small peptide substrates

Alphavirus nsP2 proteins are multifunctional and essential for viral replication. The protease role of nsP2 is critical for virus replication as only the virus protease activity is used for processing of the viral non-structural polypeptide. Chikungunya virus is an emerging disease problem that is b...

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Библиографические подробности
Опубликовано в: :Biosci Rep
Главные авторы: Saisawang, Chonticha, Sillapee, Pornpan, Sinsirimongkol, Kwanhathai, Ubol, Sukathida, Smith, Duncan R., Ketterman, Albert J.
Формат: Artigo
Язык:Inglês
Опубликовано: Portland Press Ltd. 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4445351/
https://ncbi.nlm.nih.gov/pubmed/26182358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20150086
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