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Structural basis for substrate specificity of alphavirus nsP2 proteases
The alphavirus nsP2 protease is essential for correct processing of the alphavirus nonstructural polyprotein (nsP1234) and replication of the viral genome. We have combined molecular dynamics simulations with our structural studies to reveal features of the nsP2 protease catalytic site and S1’-S4 su...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2923242/ https://ncbi.nlm.nih.gov/pubmed/20483643 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmgm.2010.04.005 |
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