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Chikungunya nsP2 protease is not a papain-like cysteine protease and the catalytic dyad cysteine is interchangeable with a proximal serine

Chikungunya virus is the pathogenic alphavirus that causes chikungunya fever in humans. In the last decade millions of cases have been reported around the world from Africa to Asia to the Americas. The alphavirus nsP2 protein is multifunctional and is considered to be pivotal to viral replication, a...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Saisawang, Chonticha, Saitornuang, Sawanan, Sillapee, Pornpan, Ubol, Sukathida, Smith, Duncan R., Ketterman, Albert J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4657084/
https://ncbi.nlm.nih.gov/pubmed/26597768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep17125
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