Antiproliferative gastrin/cholecystokinin receptor antagonists target the 78-kDa gastrin-binding protein.
Inhibition of colon carcinoma cell growth by the nonselective gastrin/cholecystokinin (CCK) receptor antagonists proglumide and benzotript provided evidence that gastrin functions as an autocrine growth factor. However, the molecular properties of the receptor mediating the antagonist effects have n...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1994
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44448/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8052625/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.16.7593 |
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