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Antiproliferative gastrin/cholecystokinin receptor antagonists target the 78-kDa gastrin-binding protein.
Inhibition of colon carcinoma cell growth by the nonselective gastrin/cholecystokinin (CCK) receptor antagonists proglumide and benzotript provided evidence that gastrin functions as an autocrine growth factor. However, the molecular properties of the receptor mediating the antagonist effects have n...
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
1994
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| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC44448/ https://ncbi.nlm.nih.gov/pubmed/8052625 |
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