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Inhibition of Dihydropteroate Synthetase from Escherichia coli by Sulfones and Sulfonamides
The inhibitory action of various diphenylsulfones and sulfonamides on dihydropteroate synthetase partially purified from Escherichia coli was examined. 4,4′-Diaminodiphenylsulfone (DDS; I(50) = 2 × 10(−5) M) and the monosubstituted derivatives 4-amino-4′-formamidodiphenylsulfone (I(50) = 5.8 × 10(−5...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
1973
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC444477/ https://ncbi.nlm.nih.gov/pubmed/4597736 |
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