Inhibition of Dihydropteroate Synthetase from Escherichia coli by Sulfones and Sulfonamides
The inhibitory action of various diphenylsulfones and sulfonamides on dihydropteroate synthetase partially purified from Escherichia coli was examined. 4,4′-Diaminodiphenylsulfone (DDS; I(50) = 2 × 10(−5) M) and the monosubstituted derivatives 4-amino-4′-formamidodiphenylsulfone (I(50) = 5.8 × 10(−5...
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| Publicado no: | Antimicrob Agents Chemother |
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| Principais autores: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
1973
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC444477/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4597736/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.3.6.665 |
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