Structure of an APC3-APC16 complex: Insights into assembly of the Anaphase Promoting Complex/Cyclosome

The Anaphase Promoting Complex/Cyclosome (APC/C) is a massive E3 ligase that controls mitosis by catalyzing ubiquitination of key cell cycle regulatory proteins. The APC/C assembly contains two subcomplexes: the “Platform” centers around a cullin-RING-like E3 ligase catalytic core; the “Arc Lamp” is...

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Gepubliceerd in:J Mol Biol
Hoofdauteurs: Yamaguchi, Masaya, Yu, Shanshan, Qiao, Renping, Weissmann, Florian, Miller, Darcie J., VanderLinden, Ryan, Brown, Nicholas G., Frye, Jeremiah J., Peters, Jan-Michael, Schulman, Brenda A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4444369/
https://ncbi.nlm.nih.gov/pubmed/25490258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2014.11.020
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