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Cell extrinsic alterations in splenic B cell maturation in Flt3-ligand knockout mice
B lymphopoiesis in bone marrow (BM) is critical for maintaining a diverse peripheral B cell pool to fight infection and establish lifelong immunity. The generation of immature B cells is reduced in Flt3-ligand (FL-/-) mice leading to deficiencies in splenic B cells. Here, we sought to understand the...
Gespeichert in:
| Veröffentlicht in: | Immun Inflamm Dis |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BlackWell Publishing Ltd
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4444153/ https://ncbi.nlm.nih.gov/pubmed/26029370 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iid3.54 |
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