Cell extrinsic alterations in splenic B cell maturation in Flt3-ligand knockout mice

B lymphopoiesis in bone marrow (BM) is critical for maintaining a diverse peripheral B cell pool to fight infection and establish lifelong immunity. The generation of immature B cells is reduced in Flt3-ligand (FL-/-) mice leading to deficiencies in splenic B cells. Here, we sought to understand the...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Immun Inflamm Dis
Asıl Yazarlar: Dolence, Joseph J, Gwin, Kimberly A, Shapiro, Mariya B, Hsu, Fan-Chi, Shapiro, Virginia S, Medina, Kay L
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BlackWell Publishing Ltd 2015
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4444153/
https://ncbi.nlm.nih.gov/pubmed/26029370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iid3.54
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