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Hoxa9 and Flt3 signaling synergistically regulate an early checkpoint in lymphopoiesis
Hoxa9 and Flt3 signaling are individually important for the generation of lymphoid lineage precursors from multipotent hematopoietic progenitors (MPP) in bone marrow (BM). Mice deficient for Hoxa9, Flt3, or Flt3-ligand (FL) have reduced numbers of lymphoid-primed multipotential progenitors (LMPP), c...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3702669/ https://ncbi.nlm.nih.gov/pubmed/23772038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1203294 |
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