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Flt3 signaling regulates the proliferation, survival, and maintenance of multipotent hematopoietic progenitors that generate B cell precursors

Flt3 signaling plays a crucial role in regulating the survival and differentiation of lymphoid progenitors into B cell precursors (BCPs) in bone marrow. To define further the role of Flt3 signaling in lymphoid progenitor survival, mice deficient in Flt3 ligand that also expressed a Bcl2 transgene (E...

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Detalhes bibliográficos
Main Authors: Dolence, Joseph J., Gwin, Kimberly A., Shapiro, Mariya B., Medina, Kay L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4089881/
https://ncbi.nlm.nih.gov/pubmed/24444745
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2014.01.001
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