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Limiting Reactions in Activation of Acyl Units in Biosynthesis of Macrolide Antibiotics

Formation of propionyl phosphate in Streptomyces erythreus synthesizing a polypropionate erythronolide ring of erythromycin was found to be catalyzed by a specific propionate kinase. The isolated and 100-fold purified kinase was devoid of activity towards acetate and other monocarboxylic acids. The...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Raczyńska-Bojanowska, Konstancja, Ruczaj, Zbigniew, Sawnor-Korszyńska, Danuta, Rafalski, Andrzej
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1973
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC444381/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4790583/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.3.2.162
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