Cloning genes for the biosynthesis of a macrolide antibiotic.

Macrocin-O-methyltransferase (MacOMeTase) catalyzes the final enzymatic step in the biosynthesis of tylosin in Streptomyces fradiae. A 44-base mixed oligonucleotide probe containing only guanosine and cytidine in the third position of degenerate codons was synthesized based on the amino acid sequenc...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Fishman, S E, Cox, K, Larson, J L, Reynolds, P A, Seno, E T, Yeh, W K, Van Frank, R, Hershberger, C L
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1987
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299519/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3479787/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.23.8248
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