Cloning genes for the biosynthesis of a macrolide antibiotic.

Macrocin-O-methyltransferase (MacOMeTase) catalyzes the final enzymatic step in the biosynthesis of tylosin in Streptomyces fradiae. A 44-base mixed oligonucleotide probe containing only guanosine and cytidine in the third position of degenerate codons was synthesized based on the amino acid sequenc...

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Detalhes bibliográficos
Main Authors: Fishman, S E, Cox, K, Larson, J L, Reynolds, P A, Seno, E T, Yeh, W K, Van Frank, R, Hershberger, C L
Formato: Artigo
Idioma:Inglês
Publicado em: 1987
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC299519/
https://ncbi.nlm.nih.gov/pubmed/3479787
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