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Quantitative detection of DNMT3A R882H mutation in acute myeloid leukemia
BACKGROUND: DNMT3A mutations represent one of the most frequent gene alterations detectable in acute myeloid leukemia (AML) with normal karyotype. Although various recurrent somatic mutations of DNMT3A have been described, the most common mutation is located at R882 in the methyltransferase domain o...
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| Publicado no: | J Exp Clin Cancer Res |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4443651/ https://ncbi.nlm.nih.gov/pubmed/25994761 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-015-0173-2 |
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