Recurrent DNMT3A R882 Mutations in Chinese Patients with Acute Myeloid Leukemia and Myelodysplastic Syndrome

Somatic mutations of DNMT3A gene have recently been reported in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS). We examined the entire coding sequences of DNMT3A gene by high-resolution melting analysis and sequencing in Chinese patients with myeloid malignancies. R882 mutations wer...

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Detalhes bibliográficos
Main Authors: Lin, Jiang, Yao, Dong-ming, Qian, Jun, Chen, Qin, Qian, Wei, Li, Yun, Yang, Jing, Wang, Cui-zhu, Chai, Hai-yan, Qian, Zhen, Xiao, Gao-fei, Xu, Wen-rong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204995/
https://ncbi.nlm.nih.gov/pubmed/22066015
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026906
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