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Histone deacetylase 10 suppresses proliferation and invasion by inhibiting the phosphorylation of β-catenin and serves as an independent prognostic factor for human clear cell renal cell carcinoma

Objective: Histone deacetylase (HDAC) is a tumor suppressor gene in various carcinomas; however, the effect of HDAC10 on human renal cell carcinoma (RCC) remains unknown. In the current study we analyzed the expression and function of HDAC10 in human clear cell RCC. Methods: RCC tissues from 145 pat...

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Detalhes bibliográficos
Publicado no:Int J Clin Exp Med
Main Authors: Fan, Wenxing, Huang, Jie, Xiao, Hua
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4443103/
https://ncbi.nlm.nih.gov/pubmed/26064269
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