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Histone Deacetylase 7 (Hdac7) Suppresses Chondrocyte Proliferation and β-Catenin Activity during Endochondral Ossification

Histone deacetylases (Hdacs) regulate endochondral ossification by suppressing gene transcription and modulating cellular responses to growth factors and cytokines. We previously showed that Hdac7 suppresses Runx2 activity and osteoblast differentiation. In this study, we examined the role of Hdac7...

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Vydáno v:J Biol Chem
Hlavní autoři: Bradley, Elizabeth W., Carpio, Lomeli R., Olson, Eric N., Westendorf, Jennifer J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4281714/
https://ncbi.nlm.nih.gov/pubmed/25389289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.596247
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