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Histone Deacetylase 7 (Hdac7) Suppresses Chondrocyte Proliferation and β-Catenin Activity during Endochondral Ossification

Histone deacetylases (Hdacs) regulate endochondral ossification by suppressing gene transcription and modulating cellular responses to growth factors and cytokines. We previously showed that Hdac7 suppresses Runx2 activity and osteoblast differentiation. In this study, we examined the role of Hdac7...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Bradley, Elizabeth W., Carpio, Lomeli R., Olson, Eric N., Westendorf, Jennifer J.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4281714/
https://ncbi.nlm.nih.gov/pubmed/25389289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.596247
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