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Histone Deacetylase Inhibitors Inhibit the Proliferation of Gallbladder Carcinoma Cells by Suppressing AKT/mTOR Signaling

Gallbladder carcinoma is an aggressive malignancy with high mortality mainly due to the limited potential for curative resection and its resistance to chemotherapeutic agents. Here, we show that the histone deacetylase inhibitors (HDACIs) trichostatin-A (TSA) and suberoylanilide hydroxamic acid (SAH...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Zhang, Peng, Guo, Zhiyong, Wu, Ying, Hu, Ronglin, Du, Jun, He, Xiaoshun, Jiao, Xingyuan, Zhu, Xiaofeng
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4542213/
https://ncbi.nlm.nih.gov/pubmed/26287365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0136193
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