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Serum Protein Binding of the Aminoglycoside Antibiotics

The binding of four aminoglycoside antibiotics by human serum was investigated under controlled conditions of physiological pH and temperature, by means of an ultrafiltration technique. No serum binding was demonstrable for gentamicin, tobramycin, or kanamycin, whereas streptomycin was 35% bound. Pr...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Principais autores: Gordon, Ralph C., Regamey, Claude, Kirby, William M. M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1972
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC444293/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4790560/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.2.3.214
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