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Serum Protein Binding of the Aminoglycoside Antibiotics

The binding of four aminoglycoside antibiotics by human serum was investigated under controlled conditions of physiological pH and temperature, by means of an ultrafiltration technique. No serum binding was demonstrable for gentamicin, tobramycin, or kanamycin, whereas streptomycin was 35% bound. Pr...

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Detalhes bibliográficos
Main Authors: Gordon, Ralph C., Regamey, Claude, Kirby, William M. M.
Formato: Artigo
Idioma:Inglês
Publicado em: 1972
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC444293/
https://ncbi.nlm.nih.gov/pubmed/4790560
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