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Serum Protein Binding of the Aminoglycoside Antibiotics

The binding of four aminoglycoside antibiotics by human serum was investigated under controlled conditions of physiological pH and temperature, by means of an ultrafiltration technique. No serum binding was demonstrable for gentamicin, tobramycin, or kanamycin, whereas streptomycin was 35% bound. Pr...

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Bibliografske podrobnosti
izdano v:Antimicrob Agents Chemother
Principais autores: Gordon, Ralph C., Regamey, Claude, Kirby, William M. M.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 1972
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC444293/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4790560/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.2.3.214
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